The overall objective of the cardiovascular disease (CVD) epidemiology and prevention postdoctoral training program at Northwestern University is to prepare academically-oriented MD and PhD trained investigators from diverse scientific and racial/ethnic backgrounds for research-intensive careers in CVD epidemiology and prevention. This ongoing multi-disciplinary research training program (now in Year 14) proposes to continue supporting 4 postdoctoral trainees for a training period that is typically 2 years in duration. At the completion of training, our alumni will be prepared for independent research careers in many sectors including academia, government, public or private industry. We will achieve this outcome by providing training in epidemiology, prevention, biostatistics, nutrition, behavioral medicine, vascular medicine, endocrinology, cardiovascular imaging, health services research, dissemination and implementation, applied genetics, transcriptomics, proteomics and metabolomics. Mentored research experiences are complemented by coursework chosen as needed individually for each trainee. Growth in knowledge, skills, attitudes and behaviors is guided by an individual development plan (IDP) prepared by each trainee and reviewed regularly with the mentoring team comprised of at least 2 highly experienced mentors. The centerpiece of the training program remains the completion of mentored research projects that yield scientific products (e.g., publications) in any of the above areas. The home for the training program remains a resource-rich environment that is home to multiple large- scale CVD cohort studies that permit immediate scientific productivity. Three primary innovations for this training period include: 1) an expansion of our program focus from traditional epidemiologic and biostatistical cohort studies and designs to address contemporary challenges in cardiovascular health; 2) the implementation of competency-based training curriculum; and, 3) an expanded approach to evaluating program outcomes. Trainees are drawn from clinical backgrounds (primarily MD intending to pursue a physician/scientist career in cardiovascular medicine and preventive cardiology) and research backgrounds (PhD in biostatistics, epidemiology, nutrition, or other related fields). We intend to continue our successful active approaches to recruiting and retaining underrepresented minority investigators. The Program Director, Associate Director, and mentors are a highly experienced group that has worked together for many years which will help to assure coordinated training. The Directors are supported by an administrative infrastructure that provides input on the program vision and mission, selection of trainees and curriculum. Ongoing evaluation allows for programmatic modifications in order to maximize the effectiveness of the program. Using these approaches, we expect to continue our success in response to the NHLBI call to establish ?a diverse scientific workforce equipped with the relevant skills, knowledge and resources to tackle future HLBS [Heart, Lung, Blood and Sleep] challenges.?

Public Health Relevance

The objective of this renewal application is to prepare 4 academically-oriented MD and PhD-trained investigators for research-intensive careers in cardiovascular disease (CVD) epidemiology and prevention. We will accomplish this over a 2-year training period through a combination of mentored research activities, coursework and seminars/workshops led by accomplished senior researchers at Northwestern University.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL069771-18
Application #
10104366
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Coady, Sean
Project Start
2003-07-01
Project End
2024-01-31
Budget Start
2021-02-01
Budget End
2022-01-31
Support Year
18
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Patel, Ravi B; Vaduganathan, Muthiah; Bhatt, Deepak L et al. (2018) Characterizing High-Performing Articles by Altmetric Score in Major Cardiovascular Journals. JAMA Cardiol :
Akhabue, Ehimare; Perak, Amanda M; Chan, Cheeling et al. (2018) Racial Differences in Rates of Change of Childhood Body Mass Index and Blood Pressure Percentiles. J Pediatr 202:98-105.e6
Mayne, Stephanie L; Pool, Lindsay R; Grobman, William A et al. (2018) Associations of neighbourhood crime with adverse pregnancy outcomes among women in Chicago: analysis of electronic health records from 2009 to 2013. J Epidemiol Community Health 72:230-236
Mayne, Stephanie L; Jose, Angelina; Mo, Allison et al. (2018) Neighborhood Disorder and Obesity-Related Outcomes among Women in Chicago. Int J Environ Res Public Health 15:
Perak, Amanda M; Marino, Bradley S; de Ferranti, Sarah D (2018) Squaring the Curve of Cardiovascular Health From the Beginning of Life. Pediatrics 141:
Bancks, Michael P; Auer, Reto; Carr, J Jeffrey et al. (2018) Self-reported marijuana use over 25 years and abdominal adiposity: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Addiction 113:689-698
Patel, Ravi B; Vaduganathan, Muthiah (2018) Targeting sudden death in heart failure with preserved ejection fraction: promise or pipedream? Expert Rev Cardiovasc Ther 16:875-877
Patel, Ravi B; Shah, Sanjiv J (2018) Drug Targets for Heart Failure with Preserved Ejection Fraction: A Mechanistic Approach and Review of Contemporary Clinical Trials. Annu Rev Pharmacol Toxicol :
Greenland, Philip; Blaha, Michael J; Budoff, Matthew J et al. (2018) Coronary Calcium Score and Cardiovascular Risk. J Am Coll Cardiol 72:434-447
Ahmad, Faraz S; French, Benjamin; Bowles, Kathryn H et al. (2018) Incorporating patient-centered factors into heart failure readmission risk prediction: A mixed-methods study. Am Heart J 200:75-82

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