Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR042647-03
Application #
2082037
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1994-03-10
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Pharmacology
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Burnett, Joseph W; Laing, Jennifer M; Aurelian, Laure (2008) Acute skin eruptions that are positive for herpes simplex virus DNA polymerase in patients with stem cell transplantation: a new manifestation within the erythema multiforme reactive dermatoses. Arch Dermatol 144:902-7
Li, B; Smith, C C; Laing, J M et al. (2007) Overload of the heat-shock protein H11/HspB8 triggers melanoma cell apoptosis through activation of transforming growth factor-beta-activated kinase 1. Oncogene 26:3521-31
Gober, Michael D; Laing, Jennifer M; Burnett, Joseph W et al. (2007) The Herpes simplex virus gene Pol expressed in herpes-associated erythema multiforme lesions upregulates/activates SP1 and inflammatory cytokines. Dermatology 215:97-106
Sharma, B K; Smith, Cynthia C; Laing, Jennifer M et al. (2006) Aberrant DNA methylation silences the novel heat shock protein H11 in melanoma but not benign melanocytic lesions. Dermatology 213:192-9
Ono, Fumitake; Sharma, Bhuvnesh K; Smith, Cynthia C et al. (2005) CD34+ cells in the peripheral blood transport herpes simplex virus DNA fragments to the skin of patients with erythema multiforme (HAEM). J Invest Dermatol 124:1215-24
Aurelian, L (2005) HSV-induced apoptosis in herpes encephalitis. Curr Top Microbiol Immunol 289:79-111
Perkins, Dana; Gyure, Kymberly A; Pereira, Edna F R et al. (2003) Herpes simplex virus type 1-induced encephalitis has an apoptotic component associated with activation of c-Jun N-terminal kinase. J Neurovirol 9:101-11
Perkins, D; Pereira, E F R; Aurelian, L (2003) The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1. J Virol 77:1292-305
Aurelian, L; Ono, F; Burnett, J (2003) Herpes simplex virus (HSV)-associated erythema multiforme (HAEM): a viral disease with an autoimmune component. Dermatol Online J 9:1
Gober, Michael D; Smith, Cynthia C; Ueda, Kaori et al. (2003) Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells. J Biol Chem 278:37600-9

Showing the most recent 10 out of 15 publications