The prevalence of diabetes mellitus in the United States is reaching epidemic proportions and accounts for a huge national burden of morbidity, mortality, and health care expenditures. The Michigan Diabetes Research center (MDRC) builds on the 35-year experience of the Michigan Diabetes Research and Training Center (MDRTC) as a key component of the research effort to promote new discoveries and enhance scientific progress through support of cutting-edge basic and clinical research related to the etiology and complications of diabetes. The goal of the MDRC Is to establish, promote, and enhance multidisciplinary and collaborative basic biomedical and clinical research among member investigators studying diabetes, its complications, and related endocrine and metabolic disorders. The missions of the MDRC are to create an environment that supports important and innovative research; raise awareness and Interest In fundamental and clinical diabetes research at affiliated Institutions and beyond; enhance diabetes research education and training opportunities for patients, students, scientists, and clinicians; attract an retain early stage Investigators and Investigators new to diabetes research; provide core services that leverage funding and unique expertise; foster interdisciplinary collaborations, especially In the emerging areas of research, to catalyze new ideas and scientific approaches; and promote the translation of scientific discoveries from bench to bedside to community to Improve public health.
The MDRC promotes and enhances multidisciplinary and collaborative basic and clinical research relevant to diabetes, its complications, and related endocrine and metabolic disorders. This serves to accelerate the pace and improve the efficiency and cost-effectiveness of biomedical and clinical research to prevent, treat, and ultimately cure diabetes and its complications.
|Lee, Jin-Sook; Caruso, Joseph A; Hubbs, Garrett et al. (2018) Molecular architecture of mouse and human pancreatic zymogen granules: protein components and their copy numbers. Biophys Rep 4:94-103|
|Yue, Yang; Blasius, T Lynne; Zhang, Stephanie et al. (2018) Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7. J Cell Biol 217:1319-1334|
|Ammari, Zaid; Pak, Stella C; Ruzieh, Mohammed et al. (2018) Posttransplant Tacrolimus-Induced Diabetic Ketoacidosis: Review of the Literature. Case Rep Endocrinol 2018:4606491|
|Brown, Callie L; Perrin, Eliana M; Peterson, Karen E et al. (2018) Association of Picky Eating With Weight Status and Dietary Quality Among Low-Income Preschoolers. Acad Pediatr 18:334-341|
|Kimball, Andrew; Schaller, Matthew; Joshi, Amrita et al. (2018) Ly6CHi Blood Monocyte/Macrophage Drive Chronic Inflammation and Impair Wound Healing in Diabetes Mellitus. Arterioscler Thromb Vasc Biol 38:1102-1114|
|Morran, Michael P; Al-Dieri, Ali G; Nestor-Kalinoski, Andrea L et al. (2018) Insulin receptor based lymphocyte trafficking in the progression of type 1 diabetes. J Biol Methods 5:|
|Jiang, Youde; Liu, Li; Steinle, Jena J (2018) miRNA15a regulates insulin signal transduction in the retinal vasculature. Cell Signal 44:28-32|
|Montrose, Luke; Padmanabhan, Vasantha; Goodrich, Jaclyn M et al. (2018) Maternal levels of endocrine disrupting chemicals in the first trimester of pregnancy are associated with infant cord blood DNA methylation. Epigenetics 13:301-309|
|Afshinnia, Farsad; Rajendiran, Thekkelnaycke M; Wernisch, Stefanie et al. (2018) Lipidomics and Biomarker Discovery in Kidney Disease. Semin Nephrol 38:127-141|
|Rodriquez, Erik J; Livaudais-Toman, Jennifer; Gregorich, Steven E et al. (2018) Relationships between allostatic load, unhealthy behaviors, and depressive disorder in U.S. adults, 2005-2012 NHANES. Prev Med 110:9-15|
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