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The entirety of funding information.
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Molecular Mechanisms of Apoptosis in Myocardial IschemiaThe long term goal of this proposal is to elucidate the mechanisms of cardiomyocyte apoptosis following ischemia/reperfusion and its relation to the progression of ventricular remodeling and heart failure. Until...
Ldl Transport in Arteries Following Endothelial InjuryCharacteristic features of early atherosclerotic lesions are lipid-filled macrophages, extracellular lipid, and localization of lesions to arterial branches or highly curved arteries. At lesion-prone sites, endothelial permeability to low density...
Nathan Shock Aging Center Microbial Composition of Developing Dental PlaqueThe long-term objective of this grant is to study the microbial composition of developing dental plaque. A predominant cultural study will compare the microbiota of sites with no attachment loss...
Drug-eluting fibers for on-demand and extended protection against HIVOral pre-exposure prophylaxis (PrEP) has transformed the field of HIV prevention, but rigorous adherence to daily drug regiments is required to achieve protective efficacy.1-3 Disproportionate efficacy of oral PrEP in...
Noncoding DNA regulatory elements and Anopheles vector biology?The highest global malaria prevalence is in Africa, where the most important vectors are members of the Anopheles gambiae species complex, including the widespread Anopheles coluzzii. Our long-term goal is...
Double-stranded RNA during DNA virus infectionDouble-stranded (ds) RNA is an early danger signal that alerts the host to viral invasion and activates several innate immune pathways that limit virus replication. These pathways include type I...
Targeting lipopolysaccharide transport machinery in Pseudomonas aeruginosaPseudomonas aeruginosa poses a major threat to human health due to limited treatment options and its ability to become resistant to antibiotics. P. aeruginosa and other Gram-negative bacteria are particularly...
The postdoctoral training period is nearly essential for all research scientists who aspire to lead a research laboratory in a university or non-profit research center. To characterize the transition of scientists from postdoc to established PI, we previously conducted an analysis of how many postdocs with a NIH-sponsored F32 fellowship went on to become PIs of a R-esearch grant. In 2006, NIH int...
Previously, we calculated the fraction of the R01 grant pool that each institution has obtained in 2013, and how this fraction has changed over time. We now wanted to perform a complementary analysis, determining institutional variability in the length of time that individual PIs are able to maintain NIH grant funding. This analysis would be of interest to university administrators who want to rec...
In our database, for any grant we report "Related Projects" that are renewals of ongoing projects from individual investigators. We wanted to improve this by identifying "Related Projects" more generally in which we group different grants based on the text in the abstract. We analyzed the similarities of 2013 NIH grant abstracts with lengths of at least 100 words (disregarding the public health r...
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